diff --git a/bigquery/google/cloud/bigquery/_http.py b/bigquery/google/cloud/bigquery/_http.py
index 5dd660ea0b8d..dd0d9d01c9de 100644
--- a/bigquery/google/cloud/bigquery/_http.py
+++ b/bigquery/google/cloud/bigquery/_http.py
@@ -29,7 +29,7 @@ class Connection(_http.JSONConnection):
     :param client_info: (Optional) instance used to generate user agent.
     """
 
-    DEFAULT_API_ENDPOINT = "https://www.googleapis.com"
+    DEFAULT_API_ENDPOINT = "https://bigquery.googleapis.com"
 
     def __init__(self, client, client_info=None, api_endpoint=DEFAULT_API_ENDPOINT):
         super(Connection, self).__init__(client, client_info)
diff --git a/bigquery/google/cloud/bigquery/client.py b/bigquery/google/cloud/bigquery/client.py
index bcc93c0b7273..103645597515 100644
--- a/bigquery/google/cloud/bigquery/client.py
+++ b/bigquery/google/cloud/bigquery/client.py
@@ -75,7 +75,7 @@
 _MAX_MULTIPART_SIZE = 5 * 1024 * 1024
 _DEFAULT_NUM_RETRIES = 6
 _BASE_UPLOAD_TEMPLATE = (
-    u"https://www.googleapis.com/upload/bigquery/v2/projects/"
+    u"https://bigquery.googleapis.com/upload/bigquery/v2/projects/"
     u"{project}/jobs?uploadType="
 )
 _MULTIPART_URL_TEMPLATE = _BASE_UPLOAD_TEMPLATE + u"multipart"
diff --git a/bigquery/tests/unit/test_client.py b/bigquery/tests/unit/test_client.py
index 3ee45f52405c..8f148c5ec7f4 100644
--- a/bigquery/tests/unit/test_client.py
+++ b/bigquery/tests/unit/test_client.py
@@ -3127,7 +3127,7 @@ def _initiate_resumable_upload_helper(self, num_retries=None):
         # Check the returned values.
         self.assertIsInstance(upload, ResumableUpload)
         upload_url = (
-            "https://www.googleapis.com/upload/bigquery/v2/projects/"
+            "https://bigquery.googleapis.com/upload/bigquery/v2/projects/"
             + self.PROJECT
             + "/jobs?uploadType=resumable"
         )
@@ -3196,7 +3196,7 @@ def _do_multipart_upload_success_helper(self, get_boundary, num_retries=None):
         get_boundary.assert_called_once_with()
 
         upload_url = (
-            "https://www.googleapis.com/upload/bigquery/v2/projects/"
+            "https://bigquery.googleapis.com/upload/bigquery/v2/projects/"
             + self.PROJECT
             + "/jobs?uploadType=multipart"
         )
diff --git a/bigquery/tests/unit/test_job.py b/bigquery/tests/unit/test_job.py
index 98090a5257fd..b34184f00cd9 100644
--- a/bigquery/tests/unit/test_job.py
+++ b/bigquery/tests/unit/test_job.py
@@ -73,7 +73,7 @@ def _make_job_resource(
     started=False,
     ended=False,
     etag="abc-def-hjk",
-    endpoint="https://www.googleapis.com",
+    endpoint="https://bigquery.googleapis.com",
     job_type="load",
     job_id="a-random-id",
     project_id="some-project",
@@ -1022,7 +1022,7 @@ class _Base(object):
     from google.cloud.bigquery.dataset import DatasetReference
     from google.cloud.bigquery.table import TableReference
 
-    ENDPOINT = "https://www.googleapis.com"
+    ENDPOINT = "https://bigquery.googleapis.com"
     PROJECT = "project"
     SOURCE1 = "http://example.com/source1.csv"
     DS_ID = "dataset_id"